BDBM50286908 (2R,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl)-2-phenoxymethyl-pentanoic acid::CHEMBL37539

SMILES OC(=O)CNC(=O)[C@@H](C[C@H](COc1ccccc1)C(O)=O)Cc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=CXWNRJVOFAKQLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286908   

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286908((2R,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50: 5.90nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50286908((2R,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50: 5.90nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP) from rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article