BDBM50286990 2-Hydroxy-5-[4-hydroxy-5-(2-isopropyl-phenylsulfanyl)-6-oxo-6H-pyran-2-yl]-benzoic acid ethyl ester::CHEMBL13036

SMILES CCOC(=O)c1cc(ccc1O)-c1cc(O)c(Sc2ccccc2C(C)C)c(=O)o1

InChI Key InChIKey=XFAVRKXROVSQIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286990   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50286990(2-Hydroxy-5-[4-hydroxy-5-(2-isopropyl-phenylsulfan...)
Affinity DataIC50: 148nMpH: 4.7Assay Description:Inhibitory activity against purified HIV-1 protease (BH10) at a pH of 4.7 and a final enzyme concentration of 0.45-1.1 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article