BDBM50287139 2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-3-(4-hydroxy-phenyl)-propionic acid::CHEMBL278754

SMILES OC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=XIYLRLVVCIVYNV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287139   

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287139(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of neutral endopeptidase in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287139(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of neutral endopeptidase in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287139(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287139(2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phe...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article