BDBM50287558 CHEMBL1333494

SMILES Cc1ccc(NS(=O)(=O)c2cc(ccc2C)C(=O)NCc2cccnc2)cc1

InChI Key InChIKey=BOTSTVSJFTXAMF-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287558   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50287558(CHEMBL1333494)Copy SMILESCopy InChI

Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2020
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50287558(CHEMBL1333494)Copy SMILESCopy InChI

Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL