BDBM50287800 5-{2-[(R)-2-((S)-2-Hydroxy-3-phenoxy-propylamino)-propyl]-thiazol-5-yl}-pentanoic acid::CHEMBL419085

SMILES C[C@H](Cc1ncc(CCCCC(O)=O)s1)NC[C@H](O)COc1ccccc1

InChI Key InChIKey=NMTNMGBESHYBOM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287800   

TargetBeta-2 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287800(5-{2-[(R)-2-((S)-2-Hydroxy-3-phenoxy-propylamino)-...)
Affinity DataKi:  150nMAssay Description:Compound was tested for its binding affinity against beta2 adrenergic receptor in CHO cell membrane using [125I]iodocyanopindolol as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-3 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287800(5-{2-[(R)-2-((S)-2-Hydroxy-3-phenoxy-propylamino)-...)
Affinity DataKi:  390nMAssay Description:Compound was tested for its ability to stimulate adenylyl cyclase activity in CHO Beta-3 adrenergic receptor cell membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-1 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287800(5-{2-[(R)-2-((S)-2-Hydroxy-3-phenoxy-propylamino)-...)
Affinity DataKi:  440nMAssay Description:Compound was tested for its binding affinity against Beta-1 adrenergic receptor in CHO cell membrane using [125I]iodocyanopindolol as the radioligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article