BDBM50287987 CHEMBL4167230

SMILES N=C(N)Nc1cccc(C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)NCCc2c[nH]c3ccccc23)c1

InChI Key InChIKey=KTPKPDHZXPMGRV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287987   

TargetIntegrin alpha-V/beta-3(Human)
University of Naples Federico II

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287987BDBM50287987(CHEMBL4167230)
Affinity DataIC50: 4nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2020
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287987BDBM50287987(CHEMBL4167230)
Affinity DataIC50: 36nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287987BDBM50287987(CHEMBL4167230)
Affinity DataIC50: 308nMAssay Description:Displacement of p53 from MDM2 in human U87MG cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2020
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
University of Naples Federico II

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287987BDBM50287987(CHEMBL4167230)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of p53 from MDM4 in human SHSY-5Y cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2020
Entry Details Article
PubMed