BDBM50288287 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-4,4-dimethyl-cyclobut-2-enone::CHEMBL91832

SMILES CC1(C)C(=O)C(=C1c1ccc(cc1)S(C)(=O)=O)c1ccc(F)cc1

InChI Key InChIKey=BIKVSCVPZGXPRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288287   

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288287(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-4...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288287(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-4...)
Affinity DataIC50: 370nMAssay Description:Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article