BDBM50288288 3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclobut-2-enone::CHEMBL328003

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)C1)c1ccccc1

InChI Key InChIKey=KSLKJFIICOYAEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288288   

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288288(3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclobut-2-e...)
Affinity DataIC50: 110nMAssay Description:Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288288(3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclobut-2-e...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article