BDBM50288328 4-(8-Fluoro-7-methoxy-4-oxo-3-trifluoromethyl-4,5-dihydro-4lambda*4*-isothiochromeno[4,3-c]pyrazol-1-yl)-benzenesulfonamide::CHEMBL94274

SMILES COc1cc2CS(=O)c3c(nn(c3-c2cc1F)-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=FRIIUWRGBWUBIL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50288328   

LigandPNGBDBM50288328(4-(8-Fluoro-7-methoxy-4-oxo-3-trifluoromethyl-4,5-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

LigandPNGBDBM50288328(4-(8-Fluoro-7-methoxy-4-oxo-3-trifluoromethyl-4,5-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288328(4-(8-Fluoro-7-methoxy-4-oxo-3-trifluoromethyl-4,5-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article