BDBM50288332 4-(3-Trifluoromethyl-4H-chromeno[4,3-c]pyrazol-1-yl)-benzenesulfonamide::CHEMBL95021

SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(c2COc3ccccc3-c12)C(F)(F)F

InChI Key InChIKey=ARDUNDMCGGZTSG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50288332   

TargetProstaglandin G/H synthase 2(Human)
Devi Ahilya Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50288332(4-(3-Trifluoromethyl-4H-chromeno[4,3-c]pyrazol-1-y...)
Affinity DataIC50: 1.32E+3nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Devi Ahilya Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50288332(4-(3-Trifluoromethyl-4H-chromeno[4,3-c]pyrazol-1-y...)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
Devi Ahilya Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50288332(4-(3-Trifluoromethyl-4H-chromeno[4,3-c]pyrazol-1-y...)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288332(4-(3-Trifluoromethyl-4H-chromeno[4,3-c]pyrazol-1-y...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288332(4-(3-Trifluoromethyl-4H-chromeno[4,3-c]pyrazol-1-y...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of COX-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article