BDBM50288333 4-(8-Fluoro-7-methyl-3-trifluoromethyl-5H-isothiochromeno[4,3-c]pyrazol-1-yl)-benzenesulfonamide::CHEMBL94494

SMILES Cc1cc2CSc3c(nn(c3-c2cc1F)-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=DADHJCHABCTJSK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50288333   

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288333(4-(8-Fluoro-7-methyl-3-trifluoromethyl-5H-isothioc...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288333(4-(8-Fluoro-7-methyl-3-trifluoromethyl-5H-isothioc...)
Affinity DataIC50: 16nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

LigandPNGBDBM50288333(4-(8-Fluoro-7-methyl-3-trifluoromethyl-5H-isothioc...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of COX-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

LigandPNGBDBM50288333(4-(8-Fluoro-7-methyl-3-trifluoromethyl-5H-isothioc...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article