BDBM50288351 (S)-5-[(2-Mercapto-indane-2-carbonyl)-amino]-4-oxo-1,2,4,5,6,7-hexahydro-azepino[3,2,1-hi]indole-2-carboxylic acid::CHEMBL316595

SMILES OC(=O)[C@@H]1Cc2cccc3CCC(NC(=O)C4(S)Cc5ccccc5C4)C(=O)N1c23

InChI Key InChIKey=HGYGLTSWQBVWFB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288351   

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288351((S)-5-[(2-Mercapto-indane-2-carbonyl)-amino]-4-oxo...)
Affinity DataIC50: 505nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetAngiotensin-converting enzyme 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288351((S)-5-[(2-Mercapto-indane-2-carbonyl)-amino]-4-oxo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article