BDBM50288568 CHEMBL102887::{(2R,4S)-2-(3,5-Dibromo-benzyl)-4-[(quinolin-4-ylmethyl)-amino]-piperidin-1-yl}-(3,5-dimethyl-phenyl)-methanone

SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1cc(Br)cc(Br)c1)NCc1ccnc2ccccc12

InChI Key InChIKey=MQXUGPXFUUIGLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288568   

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288568({(2R,4S)-2-(3,5-Dibromo-benzyl)-4-[(quinolin-4-ylm...)
Affinity DataIC50: 52nMAssay Description:Binding affinity against NK1 receptor by displacement of [3H]SP from bovine retina membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article