BDBM50289292 2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene::CHEMBL440512

SMILES Cc1cc2c(Nc3ccccc3N=C2N2CC[N+](C)([O-])CC2)s1

InChI Key InChIKey=LJVNYCDXBXGQIK-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50289292   

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  87nMAssay Description:In vitro binding affinity of compound against histamine H1 neuronal receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  112nMAssay Description:In vitro binding affinity of compound against neuronal 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  119nMAssay Description:In vitro binding affinity of compound against neuronal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  266nMAssay Description:In vitro binding affinity of compound against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(1A) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  395nMAssay Description:In vitro binding affinity of compound against dopamine neuronal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  662nMAssay Description:In vitro binding affinity of compound against muscarinic neuronal receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of compound against neuronal alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of compound against neuronal Beta adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article