BDBM50289306 2,3-Dichloro-6-(4-chloro-phenyl)-5-(4-methanesulfonyl-phenyl)-imidazo[2,1-b]thiazole::CHEMBL149597

SMILES CS(=O)(=O)c1ccc(cc1)-c1c(nc2sc(Cl)c(Cl)n12)-c1ccc(Cl)cc1

InChI Key InChIKey=AOXNXAQQOUPNLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289306   

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289306(2,3-Dichloro-6-(4-chloro-phenyl)-5-(4-methanesulfo...)
Affinity DataIC50: 3.60E+3nMAssay Description:In vitro inhibition of the production of PGE-2 in arachidonic acid stimulated chinese hamster ovary (CHO) cells transfected with human cyclooxygenase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289306(2,3-Dichloro-6-(4-chloro-phenyl)-5-(4-methanesulfo...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vivo ability to inhibit cyclooxygenase-1 enzyme in human whole blood was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article