BDBM50289321 5-(4-Methanesulfonyl-phenyl)-6-phenyl-2-vinyl-thiazolo[3,2-b][1,2,4]triazole::CHEMBL157714

SMILES CS(=O)(=O)c1ccc(cc1)-c1sc2nc(C=C)nn2c1-c1ccccc1

InChI Key InChIKey=NDKYEPMSJMCRHM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50289321   

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289321(5-(4-Methanesulfonyl-phenyl)-6-phenyl-2-vinyl-thia...)
Affinity DataIC50: 6nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 2 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289321(5-(4-Methanesulfonyl-phenyl)-6-phenyl-2-vinyl-thia...)
Affinity DataIC50: 4.10E+3nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289321(5-(4-Methanesulfonyl-phenyl)-6-phenyl-2-vinyl-thia...)
Affinity DataIC50: 9.60E+3nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289321(5-(4-Methanesulfonyl-phenyl)-6-phenyl-2-vinyl-thia...)
Affinity DataIC50: 6.03E+6nMAssay Description:Inhibition of COX2 (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article