BDBM50289327 5-(4-Methanesulfonyl-phenyl)-6-m-tolyl-2-trifluoromethyl-thiazolo[3,2-b][1,2,4]triazole::CHEMBL421826

SMILES Cc1cccc(c1)-c1c(sc2nc(nn12)C(F)(F)F)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=LZOIEGWIVVWHNS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289327   

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289327(5-(4-Methanesulfonyl-phenyl)-6-m-tolyl-2-trifluoro...)
Affinity DataIC50: 3nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289327(5-(4-Methanesulfonyl-phenyl)-6-m-tolyl-2-trifluoro...)
Affinity DataIC50: 610nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289327(5-(4-Methanesulfonyl-phenyl)-6-m-tolyl-2-trifluoro...)
Affinity DataIC50: 3.02E+6nMAssay Description:Inhibition of COX2 (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article