BDBM50289561 4-tert-Butyl-benzoic acid [1-(2-hydroxy-naphthalen-1-yl)-meth-(E)-ylidene]-hydrazide::CHEMBL41643

SMILES CC(C)(C)c1ccc(cc1)C(=O)N\N=C\c1c(O)ccc2ccccc12

InChI Key InChIKey=QSEQSUVWYBZMLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289561   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Armed Police Forces Hospital of Sichuan

Curated by ChEMBL
LigandPNGBDBM50289561(4-tert-Butyl-benzoic acid [1-(2-hydroxy-naphthalen...)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptase associated RNA-dependent DNA polymerase activity incubated for 30 mins by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Armed Police Forces Hospital of Sichuan

Curated by ChEMBL
LigandPNGBDBM50289561(4-tert-Butyl-benzoic acid [1-(2-hydroxy-naphthalen...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of N-terminal 6-his-tagged HIV-1 reverse transcriptase RNase H (427 to 560 residues) transfected in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCarboxypeptidase A1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50289561(4-tert-Butyl-benzoic acid [1-(2-hydroxy-naphthalen...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibitory concentration required to inhibit carboxypeptidase A (CPA, bovine, Type I) was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article