BDBM50290195 (2H-Benzo[1,4]oxazin-3-yl)-[5-(4-pyrimidin-2-yl-piperazin-1-yl)-pentyl]-amine; compound with but-2-enedioic acid::CHEMBL80645

SMILES C(CCNC1=Nc2ccccc2OC1)CCN1CCN(CC1)c1ncccn1

InChI Key InChIKey=JTFGONAIGJAYQD-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50290195   

TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290195((2H-Benzo[1,4]oxazin-3-yl)-[5-(4-pyrimidin-2-yl-pi...)
Affinity DataKi:  19nMAssay Description:Binding affinity at cloned human D4 dopamine receptor in CHO cells using [3H]-YM 09151 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290195((2H-Benzo[1,4]oxazin-3-yl)-[5-(4-pyrimidin-2-yl-pi...)
Affinity DataIC50: 95nMAssay Description:Binding affinity at cloned human D4 dopamine receptor in CHO cells using [3H]-YM 09151 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290195((2H-Benzo[1,4]oxazin-3-yl)-[5-(4-pyrimidin-2-yl-pi...)
Affinity DataKi:  1.81E+3nMAssay Description:Binding affinity at cloned human D3 dopamine receptor in CHO cells using [3H]-YM 09151 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290195((2H-Benzo[1,4]oxazin-3-yl)-[5-(4-pyrimidin-2-yl-pi...)
Affinity DataKi:  2.54E+3nMAssay Description:Binding affinity at cloned human D2 dopamine receptor in CHO cells using [3H]-YM 09151 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article