BDBM50290246 CHEMBL80128::{3-Benzyl-1-[((S)-1-carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-2-oxo-azepan-3-yl}-carbamic acid methyl ester; TFA

SMILES COC(=O)NC1(Cc2ccccc2)CCCCN(CC(=O)N[C@H]2CCCN(C2O)C(N)=N)C1=O

InChI Key InChIKey=UXGCIUULQGWSBE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50290246   

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290246({3-Benzyl-1-[((S)-1-carbamimidoyl-2-hydroxy-piperi...)
Affinity DataIC50: 466nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290246({3-Benzyl-1-[((S)-1-carbamimidoyl-2-hydroxy-piperi...)
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290246({3-Benzyl-1-[((S)-1-carbamimidoyl-2-hydroxy-piperi...)
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article