BDBM50290328 CHEMBL87318::[(5S,8S,14S,22R,24aS)-22-Carbamoyl-14-(3-guanidino-propyl)-5-(1H-indol-3-ylmethyl)-21,21-dimethyl-4,7,10,13,16,24-hexaoxo-docosahydro-19,20-dithia-3a,6,9,12,15,23-hexaaza-cyclopentacyclotricosen-8-yl]-acetic acid

SMILES CC1(C)SSCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N2CCC[C@H]2C(=O)N[C@@H]1C(N)=O

InChI Key InChIKey=PIYMZSDMOHRSGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290328   

TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290328([(5S,8S,14S,22R,24aS)-22-Carbamoyl-14-(3-guanidino...)
Affinity DataIC50: 100nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta-3 integrin by 50% in an ELISA testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290328([(5S,8S,14S,22R,24aS)-22-Carbamoyl-14-(3-guanidino...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article