BDBM50290708 CHEMBL94834::[3-(2-{4-[1-(4-Fluoro-benzyl)-1H-benzoimidazole-2-carbonyl]-piperidin-1-yl}-ethyl)-3-(4-trifluoromethyl-phenyl)-pyrrolidin-1-yl]-(3,4,5-trimethoxy-phenyl)-methanone

SMILES COc1cc(cc(OC)c1OC)C(=O)N1CCC(CCN2CCC(CC2)C(=O)c2nc3ccccc3n2Cc2ccc(F)cc2)(C1)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=BEYBSSSCFNIKNG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50290708   

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290708([3-(2-{4-[1-(4-Fluoro-benzyl)-1H-benzoimidazole-2-...)
Affinity DataIC50: 6.30nMAssay Description:Antagonistic activity against histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSubstance-P receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290708([3-(2-{4-[1-(4-Fluoro-benzyl)-1H-benzoimidazole-2-...)
Affinity DataIC50: 6.90nMAssay Description:Antagonistic activity against Tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSubstance-P receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290708([3-(2-{4-[1-(4-Fluoro-benzyl)-1H-benzoimidazole-2-...)
Affinity DataIC50: 117nMAssay Description:Antagonism of the guinea pig tachykinin NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290708([3-(2-{4-[1-(4-Fluoro-benzyl)-1H-benzoimidazole-2-...)
Affinity DataIC50: 473nMAssay Description:Antagonism of the human histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article