BDBM50290958 CHEMBL318017::N-[2-Benzo[1,3]dioxol-5-yl-2-(6-oxo-3-propyl-6H-pyridazin-1-yl)-acetyl]-4-isopropyl-benzenesulfonamide

SMILES CCCc1ccc(=O)n(n1)C(C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2OCOc2c1

InChI Key InChIKey=NLWXTHVZOHIXKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290958   

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290958(N-[2-Benzo[1,3]dioxol-5-yl-2-(6-oxo-3-propyl-6H-py...)
Affinity DataIC50: 640nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290958(N-[2-Benzo[1,3]dioxol-5-yl-2-(6-oxo-3-propyl-6H-py...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to endothelin B receptor of porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article