BDBM50291756 2-Propylamino-benzo[d][1,3]oxazin-4-one::CHEMBL343478

SMILES CCCNc1nc2ccccc2c(=O)o1

InChI Key InChIKey=QTUULNVXRXRNIL-UHFFFAOYSA-N

Data  2 KI  2 Koff  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50291756   

TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291756(2-Propylamino-benzo[d][1,3]oxazin-4-one | CHEMBL34...)
Affinity DataKi:  91nMAssay Description:Binding affinity against human leukocyte elastase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291756(2-Propylamino-benzo[d][1,3]oxazin-4-one | CHEMBL34...)
Affinity DataKi:  100nM Kon:  0.0407M-1s-1 Koff:  4.47E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291756(2-Propylamino-benzo[d][1,3]oxazin-4-one | CHEMBL34...)
Affinity DataKon:  0.0410M-1s-1Assay Description:Rate of deacylation by human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2010
Entry Details Article
PubMed