BDBM50291790 1-[3-(Biphenyl-3-yloxymethyl)-phenyl]-6,6-dimethyl-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL20424

SMILES CC1(C)N=C(N)N=C(N)N1c1cccc(COc2cccc(c2)-c2ccccc2)c1

InChI Key InChIKey=ZDWRGSYMUVYIQJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50291790   

TargetDihydrofolate reductase(Pneumocystis carinii)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50291790(1-[3-(Biphenyl-3-yloxymethyl)-phenyl]-6,6-dimethyl...)
Affinity DataKi:  4.47nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
LigandPNGBDBM50291790(1-[3-(Biphenyl-3-yloxymethyl)-phenyl]-6,6-dimethyl...)
Affinity DataKi:  17.0nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Leishmania majorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
TBA

Curated by ChEMBL
LigandPNGBDBM50291790(1-[3-(Biphenyl-3-yloxymethyl)-phenyl]-6,6-dimethyl...)
Affinity DataKi:  162nMAssay Description:Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50291790(1-[3-(Biphenyl-3-yloxymethyl)-phenyl]-6,6-dimethyl...)
Affinity DataKi:  204nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed