BDBM50292245 CHEMBL4168177

SMILES CN1CCN(CC1)c1cc(Nc2cc(C)[nH]n2)nc(Nc2ccc(F)c(Cl)c2)n1

InChI Key InChIKey=NKQFVOKSVRQZKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292245   

TargetAurora kinase A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50292245(CHEMBL4168177)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of AURKA (unknown origin) using FAM-labeled peptide substrate preincubated for 10 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50292245(CHEMBL4168177)
Affinity DataIC50: 26nMAssay Description:Inhibition of AURKB (unknown origin) using FAM-labeled peptide substrate preincubated for 10 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2020
Entry Details Article
PubMed