BDBM50292671 (+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin-1-yl)acetamide::(+/-)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin-1-yl)acetamide::(-)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin-1-yl)acetamide::CHEMBL496376

SMILES NC(=O)CN1CCCC(C1)(C1CCN(Cc2ccc(Br)cc2)CC1)c1ccccc1

InChI Key InChIKey=YPIYIPYCTOJYAU-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50292671   

TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 810nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to human muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50: 1.10E+4nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed