BDBM50293133 2-(4-{2-[2-cyclopentyl-4-hydroxy-5-(3-methoxybenzyl)-6-oxo-3,6-dihydro-2H-pyran-2-yl]ethyl}-2-fluorophenyl)-2-methylpropanenitrile::CHEMBL472914

SMILES COc1cccc(CC2C(=O)CC(CCc3ccc(c(F)c3)C(C)(C)C#N)(OC2=O)C2CCCC2)c1

InChI Key InChIKey=KIYUHIRXTZQCJQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293133   

TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50293133(2-(4-{2-[2-cyclopentyl-4-hydroxy-5-(3-methoxybenzy...)
Affinity DataIC50: 770nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed