BDBM50293138 CHEMBL523747::N-cyclopropyl-4-(6-methoxypyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine

SMILES COc1ccc2c(cnn2n1)-c1ccnc(NC2CC2)n1

InChI Key InChIKey=OJNPXUBDVGTOJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293138   

TargetCyclin-dependent kinase 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293138(N-cyclopropyl-4-(6-methoxypyrazolo[1,5-b]pyridazin...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293138(N-cyclopropyl-4-(6-methoxypyrazolo[1,5-b]pyridazin...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of GSK3-beta by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed