BDBM50293250 (S)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(pyrrolidin-2-ylethynyl)thieno[3,2-d]pyrimidin-4-amine::CHEMBL495979

SMILES Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C[C@@H]3CCCN3)cc2Cl)c1

InChI Key InChIKey=FNYHTKUCTLSINN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293250   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293250((S)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(py...)
Affinity DataIC50: 54nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293250((S)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(py...)
Affinity DataIC50: 109nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed