BDBM50293257 (3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl methanesulfonate::CHEMBL500115

SMILES CS(=O)(=O)O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1

InChI Key InChIKey=SHMDVAIGKWZURP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293257   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293257((3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)pheny...)
Affinity DataIC50: 40nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293257((3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)pheny...)
Affinity DataIC50: 81nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed