BDBM50293419 (S)-4'-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(4-chlorophenyl)acetanilide::CHEMBL563810

SMILES O[C@@H](CNCCc1ccc(NC(=O)Cc2ccc(Cl)cc2)cc1)COc1ccc(O)cc1

InChI Key InChIKey=VFZWDKCDQQXMIZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293419   

TargetBeta-1 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50293419((S)-4'-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as increase in cAMP production after 2 days by radioimmun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50293419((S)-4'-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human cloned adrenergic beta3 receptor expressed in CHO cells assessed as increase in cAMP production after 2 days by radioimmuno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50293419((S)-4'-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human cloned adrenergic beta2 receptor expressed in CHO cells assessed as increase in cAMP production after 2 days by radioimmuno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed