BDBM50293526 2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)thieno[3,2-d]pyrimidin-4-amine::CHEMBL556871

SMILES Cc1cccc(n1)-c1nc(Nc2ccncc2)c2sccc2n1

InChI Key InChIKey=WNARUZYWHVAKOP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293526   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293526(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)thieno[3,...)
Affinity DataIC50:  60nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293526(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)thieno[3,...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed