BDBM50293560 1-Methyl-1H-imidazole-4-carboxylic acid(3-methyl-3-aza-bicyclo[3.1.0]hex-6-ylmethyl)-(3-trifluoromethoxy-benzyl)-amide::CHEMBL556247

SMILES CN1C[C@H]2[C@H](CN(Cc3cccc(OC(F)(F)F)c3)C(=O)c3cn(C)cn3)[C@H]2C1

InChI Key InChIKey=AZPNIOXCMXPLKP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293560   

LigandPNGBDBM50293560(1-Methyl-1H-imidazole-4-carboxylic acid(3-methyl-3...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandPNGBDBM50293560(1-Methyl-1H-imidazole-4-carboxylic acid(3-methyl-3...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition human ERG expressed in HEK293 cells assessed as blockade of membrane current by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandPNGBDBM50293560(1-Methyl-1H-imidazole-4-carboxylic acid(3-methyl-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed