BDBM50293561 1-Methyl-1H-imidazole-4-carboxylic acid(3-cyclopentylmethyl-3-aza-bicyclo[3.1.0]hex-6-ylmethyl)-(3-trifluoromethoxy-benzyl)-amide::CHEMBL563220

SMILES Cn1cnc(c1)C(=O)N(C[C@H]1[C@@H]2CN(CC3CCCC3)C[C@H]12)Cc1cccc(OC(F)(F)F)c1

InChI Key InChIKey=DBQBAHSSKFGSRU-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293561   

LigandPNGBDBM50293561(1-Methyl-1H-imidazole-4-carboxylic acid(3-cyclopen...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandPNGBDBM50293561(1-Methyl-1H-imidazole-4-carboxylic acid(3-cyclopen...)
Affinity DataIC50: 460nMAssay Description:Inhibition human ERG expressed in HEK293 cells assessed as blockade of membrane current by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandPNGBDBM50293561(1-Methyl-1H-imidazole-4-carboxylic acid(3-cyclopen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed