BDBM50293567 1-Methyl-1H-imidazole-4-carboxylic acid(3-aza-bicyclo[3.1.0]hex-6-ylmethyl)-(3-chloro-4-fluoro-benzyl)-amide::CHEMBL560289

SMILES Cn1cnc(c1)C(=O)N(C[C@H]1[C@@H]2CNC[C@H]12)Cc1ccc(F)c(Cl)c1

InChI Key InChIKey=HTUXUNBQNWREPD-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293567   

LigandPNGBDBM50293567(1-Methyl-1H-imidazole-4-carboxylic acid(3-aza-bicy...)
Affinity DataKi:  109nMAssay Description:Binding affinity to GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandPNGBDBM50293567(1-Methyl-1H-imidazole-4-carboxylic acid(3-aza-bicy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]glycine from GlyT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandPNGBDBM50293567(1-Methyl-1H-imidazole-4-carboxylic acid(3-aza-bicy...)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition human ERG expressed in HEK293 cells assessed as blockade of membrane current by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed