BDBM50293649 (6-(2-phenylethynyl)pyridin-3-yl)(piperidin-1-yl)methanone::CHEMBL549319

SMILES O=C(N1CCCCC1)c1ccc(nc1)C#Cc1ccccc1

InChI Key InChIKey=LFGXHTODSVXJEF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293649   

TargetMetabotropic glutamate receptor 5(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50293649((6-(2-phenylethynyl)pyridin-3-yl)(piperidin-1-yl)m...)
Affinity DataEC50:  280nMAssay Description:Agonist activity at human mGluR5 transiently transfected in BHK cells assessed as potentiation of L-glutamate-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed