BDBM50293672 CHEMBL552038::N4-(5-methyl-1H-pyrazol-3-yl)-N2-phenylquinazoline-2,4-diamine

SMILES Cc1cc(Nc2nc(Nc3ccccc3)nc3ccccc23)[nH]n1

InChI Key InChIKey=MAIYDNZVOBREIJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293672   

TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293672BDBM50293672(N4-(5-methyl-1H-pyrazol-3-yl)-N2-phenylquinazoline...)
Affinity DataKi:  24nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293672BDBM50293672(N4-(5-methyl-1H-pyrazol-3-yl)-N2-phenylquinazoline...)
Affinity DataKi:  24nMAssay Description:Inhibition of Aurora-A by coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293672BDBM50293672(N4-(5-methyl-1H-pyrazol-3-yl)-N2-phenylquinazoline...)
Affinity DataKi:  393nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed