BDBM50293691 CHEMBL549469::N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2-ylthio)phenyl)acetamide

SMILES CC(=O)Nc1ccc(Sc2nccc(Nc3cc(C)n[nH]3)n2)cc1

InChI Key InChIKey=BGNRYQCGVJJPRI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293691   

TargetAurora kinase A(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293691BDBM50293691(N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2...)
Affinity DataKi:  86nMAssay Description:Inhibition of Aurora-A by coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293691BDBM50293691(N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2...)
Affinity DataKi:  207nMAssay Description:Inhibition of Aurora-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed