BDBM50293714 CHEMBL551635::N-(4-fluoro-3-methoxyphenyl)picolinamide::cid_42644786

SMILES COc1cc(NC(=O)c2ccccn2)ccc1F

InChI Key InChIKey=PPWLYNRCVNCXAA-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50293714   

TargetMetabotropic glutamate receptor 4(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50293714(CHEMBL551635 | cid_42644786 | N-(4-fluoro-3-methox...)
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50293714(CHEMBL551635 | cid_42644786 | N-(4-fluoro-3-methox...)
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50293714(CHEMBL551635 | cid_42644786 | N-(4-fluoro-3-methox...)
Affinity DataEC50:  370nMAssay Description:Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4 [Q124R](Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293714(CHEMBL551635 | cid_42644786 | N-(4-fluoro-3-methox...)
Affinity DataEC50:  374nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 4(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50293714(CHEMBL551635 | cid_42644786 | N-(4-fluoro-3-methox...)
Affinity DataEC50:  776nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 4(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50293714(CHEMBL551635 | cid_42644786 | N-(4-fluoro-3-methox...)
Affinity DataEC50:  780nMAssay Description:Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed