BDBM50293739 CHEMBL555454::N-(4-fluoro-3-(trifluoromethyl)phenyl)picolinamide::cid_44191180

SMILES Fc1ccc(NC(=O)c2ccccn2)cc1C(F)(F)F

InChI Key InChIKey=OBQCRMSWBKGCBP-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293739   

TargetMetabotropic glutamate receptor 4 [Q124R](Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293739(CHEMBL555454 | cid_44191180 | N-(4-fluoro-3-(trifl...)
Affinity DataEC50:  999nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50293739(CHEMBL555454 | cid_44191180 | N-(4-fluoro-3-(trifl...)
Affinity DataEC50:  1.00E+3nMAssay Description:Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50293739(CHEMBL555454 | cid_44191180 | N-(4-fluoro-3-(trifl...)
Affinity DataEC50:  1.50E+3nMAssay Description:Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50293739(CHEMBL555454 | cid_44191180 | N-(4-fluoro-3-(trifl...)
Affinity DataEC50:  1.53E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay