BDBM50294048 2-(3-Cyclohexyl-3-methylthioureido)-4,5-dimethylthiophene-3-carboxylic Acid::CHEMBL554134

SMILES CN(C1CCCCC1)C(=S)Nc1sc(C)c(C)c1C(O)=O

InChI Key InChIKey=MEZMTOVQURDHAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294048   

TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50294048(2-(3-Cyclohexyl-3-methylthioureido)-4,5-dimethylth...)
Affinity DataIC50: 4.19E+3nMAssay Description:Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed