BDBM50294116 CHEMBL561763::N-[3-[4-(2-Methylsulfanylphenyl)piperazin-1-yl]propyl]pyrazolo-[1,5-a]pyridine-3-carboxamide

SMILES CSc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1

InChI Key InChIKey=ZMVDAQVAKLTNRL-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50294116   

TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294116(N-[3-[4-(2-Methylsulfanylphenyl)piperazin-1-yl]pro...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294116(N-[3-[4-(2-Methylsulfanylphenyl)piperazin-1-yl]pro...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294116(N-[3-[4-(2-Methylsulfanylphenyl)piperazin-1-yl]pro...)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294116(N-[3-[4-(2-Methylsulfanylphenyl)piperazin-1-yl]pro...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294116(N-[3-[4-(2-Methylsulfanylphenyl)piperazin-1-yl]pro...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50294116(N-[3-[4-(2-Methylsulfanylphenyl)piperazin-1-yl]pro...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed