BDBM50294200 3-(6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl)propionic acid::CHEMBL549341

SMILES CC1(C)Cc2c(c(c(CCC(O)=O)n2C1)-c1ccc(Cl)cc1)-c1ccccc1

InChI Key InChIKey=ZSOORNCESLXGCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294200   

TargetProstaglandin E synthase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50294200(3-(6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of mPGES1 in IL1-beta treated human A549 cell microsomal membrane assessed as residual enzyme activity after 1 min by measuring PGE2 level...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed