BDBM50294208 CHEMBL565059::methyl 2-(2-(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimethoxyphenyl)acryloyl)-1,2-dihydrophthalazin-1-yl)-2-methylpropanoate

SMILES COC(=O)C(C)(C)C1N(N=Cc2ccccc12)C(=O)\C=C\c1cc(Cc2cnc(N)nc2N)cc(OC)c1OC

InChI Key InChIKey=SMPLMPJVQOYTOJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294208   

TargetDihydrofolate reductase(Rat)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294208(methyl 2-(2-(3-(5-((2,4-diaminopyrimidin-5-yl)meth...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294208(methyl 2-(2-(3-(5-((2,4-diaminopyrimidin-5-yl)meth...)
Affinity DataIC50: 8.13E+5nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed