BDBM50294217 3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimethoxyphenyl)-1-(1-methylphthalazin-2(1H)-yl)propan-1-one::CHEMBL564880

SMILES COc1cc(Cc2cnc(N)nc2N)cc(CCC(=O)N2N=Cc3ccccc3C2C)c1OC

InChI Key InChIKey=VBASTGYHLLRXMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294217   

TargetDihydrofolate reductase(Human)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294217(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed