BDBM50294442 CHEMBL549823::ethyl 7-(3-(4-methyl-3-(trifluoromethyl)benzamido)phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate

SMILES CCOC(=O)c1cnn2c(ccnc12)-c1cccc(NC(=O)c2ccc(C)c(c2)C(F)(F)F)c1

InChI Key InChIKey=LNEZCTJJIDDWKC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294442   

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294442(ethyl 7-(3-(4-methyl-3-(trifluoromethyl)benzamido)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed