BDBM50294453 7-(3-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenyl)-N-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide::CHEMBL541201

SMILES FC(F)(F)c1cc(NC(=O)Nc2cccc(c2)-c2ccnc3c(cnn23)C(=O)NCCN2CCOCC2)ccc1Cl

InChI Key InChIKey=FWFGUQBBFCETAJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294453   

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294453(7-(3-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed