BDBM50294580 2-(4'-(trifluoromethyl)biphenyl-4-yl)vinylboronic acid::CHEMBL561852

SMILES OB(O)\C=C\c1ccc(cc1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=OBFLJGFUDKLWLG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294580   

TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50294580(2-(4'-(trifluoromethyl)biphenyl-4-yl)vinylboronic ...)
Affinity DataKi:  9.50E+3nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50294580(2-(4'-(trifluoromethyl)biphenyl-4-yl)vinylboronic ...)
Affinity DataKi:  2.76E+4nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase(Yeast)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50294580(2-(4'-(trifluoromethyl)biphenyl-4-yl)vinylboronic ...)
Affinity DataKi:  5.21E+6nMAssay Description:Inhibition of Candida albicans recombinant Carbonic anhydrase pre-incubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed