BDBM50294697 4-((2-chlorobenzyl)(1-(1-methyl-1H-pyrazol-5-yl)ethyl)amino)-2-chlorobenzonitrile::CHEMBL564782

SMILES CC(N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1)c1ccnn1C

InChI Key InChIKey=XLMIFHQZWDWQTD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294697   

TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294697(4-((2-chlorobenzyl)(1-(1-methyl-1H-pyrazol-5-yl)et...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at progesterone receptor in human T47D cells by alkaline phosphatase release based reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294697(4-((2-chlorobenzyl)(1-(1-methyl-1H-pyrazol-5-yl)et...)
Affinity DataIC50: 25nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed